??? ???? ???? ??? ????? ??? ??? ? ?? ??? ??? ?? ??? ?????.????? ?? ?? ??? ???? ? ????? ???? ?? ???, ?? ?? ??? ????.?? ? ??? ?? ?? ???? ?? ????. ???? ?? ? ????? ?? ??? ????.?? ????? ?????? ?? ???? ?? ?? ????? ??? ??? ????? ?? ?????. ?? ??? ??? ??? ??? ???? ??? ??? ?????.????? ?? ?????? ??? ?? ??? ??? ? ????. ?? ???? ??? ???? ????? ???? ??? ? ????.??

Il trattamento con un inibitore della fosfodiesterasi di tipo 5 aumenta la quantità e la permanenza del NO in loco e quindi prolunga e accentua questo rilassamento.Tadalafil had no major impact on the pharmacokinetics of theophylline.When tadalafil was administered to subjects getting theophylline, a small augmentation (three beats per moment) of